There is hope
We are not far from the answer, but we need your help to get there
There is no cure or even a diagnostic test for MND. It can take over a year from symptom onset to confirming a diagnosis - an unacceptable delay in such a rapidly progressive condition. A condition which can leave patients unable to walk, eat and eventually breath.
The Broad Appeal is offering hope and supporting three exciting projects which will aid the understanding of this cruel condition:
Identifying a Blood Based Microrna Fingerprint for Mnd. By Emily Goodall
The aim of this project is to identify MND specific, blood-based microRNA 'fingerprints' that will be useful in diagnosis, prognosis prediction and disease monitoring.
For more information please click here
Clinical Trial of Diaphragm Pacing
Diaphragm pacing is a way of supporting breathing by supplying regular pulses of electrical stimulation to the diaphragm muscle. This project will rigorously test whether the addition of diaphragm pacing provides benefits for people with MND, in terms of survival and quality of life, over and above those provided by current standard respiratory care.
For more information click here
Using a Zebrafish Model to Understand the Early Spread of MND and to Screen Potential New Drugs
This project will involve the use of a Zebrafish Model of MND to efficiently screen over 2,000 potential drugs for any beneficial effects. The zebrafish will also provide the researchers with opportunities to study and better understand how neuronal stress develops and spreads in MND, offering insight into the earliest stages of the disease.
For more information click here
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